SubtiBank SubtiBank
spoIISB
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spoIISB

disruption blocks sporulation after septum formation
Locus
BSU_12820
Isoelectric point
10.79
Molecular weight
6.52 kDa
Protein length
56 aa Sequence Blast
Gene length
171 bp Sequence Blast
Function
sporulation
Product
anti-toxin
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Lifestyles → Sporulation → Sporulation/ other
  • Lifestyles → Coping with stress → Toxins, antitoxins and immunity against toxins
  • Lifestyles → Coping with stress → Toxins, antitoxins and immunity against toxins → Type 2 TA systems

    • Gene

    Coordinates
    1,348,442 1,348,612

    Phenotypes of a mutant

  • sporulation efficiency is reduced by four orders of magnitude PubMed

    • The protein

    Protein family

  • SpoIISB antitoxin family (single member, according to UniProt)

    • Structure

  • 3O6Q (cytoplasmic fragment of SpoIISA (CSpoIISA) in complex with SpoIISB) PubMed

    • Expression and Regulation

    Operons

    Genes
    spoIISA-spoIISB
    Description
    PubMed

    Sigma factors

  • SigK: sigma factor, in SigK regulon
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    Biological materials

    Mutant

  • 1S124 ( spoIISB::tet), PubMed, available at BGSC
  • BKE12820 (spoIISB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TCTGTTTTGAAACGCACGTT, downstream forward: _UP4_TGATCACACTAAAAGGACAA
  • BKK12820 (spoIISB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TCTGTTTTGAAACGCACGTT, downstream forward: _UP4_TGATCACACTAAAAGGACAA

    • References

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