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sigB
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sigB

RNA polymerase sigma factor SigB
Locus
BSU_04730
Isoelectric point
5.42
Molecular weight
29.99 kDa
Protein length
262 aa Sequence Blast
Gene length
789 bp Sequence Blast
Function
general stress response, biocontrol of fungal growth
Product
RNA polymerase sigma factor SigB
Essential
no
Synonyms
rpoF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → RNA synthesis and degradation → Transcription → Sigma factors
  • Information processing → Regulation of gene expression → Sigma factors and their control → Sigma factors
  • Lifestyles → Coping with stress → General stress proteins (controlled by SigB)

    • Gene

    Coordinates
    522,862 523,650

    The protein

    Protein family

  • Sigma-70 factor family (according to UniProt)

    • Effectors of protein activity

  • SigB is activated during bacterial-fungal interaction (via RsbP) PubMed

    • Structure

  • 1L0O (SigF-SpoIIAB complex from Geobacillus stearothermophilus, 32% identity) PubMed

    • Expression and Regulation

    Operons

    Genes
    rsbR-rsbS-rsbT-rsbU-rsbV-rsbW-sigB-rsbX
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigB: sigma factor, PubMed, in SigB regulon

    • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon

    • Regulation

  • rsbV: induced by stress (SigB) PubMed
    • view in new tab

    Genes
    rsbV-rsbW-sigB-rsbX
    Description
    PubMed

    Regulation

  • rsbV: induced by stress (SigB) PubMed
    • view in new tab

    Biological materials

    Mutant

  • QB5344 (cat), available in Jörg Stülke's lab
  • 1A675 ( sigB::cat), PubMed, available at BGSC
  • 1A777 ( sigB::cat), PubMed, available at BGSC
  • 1A780 ( sigB::spec), PubMed, available at BGSC
  • BKE04730 (sigB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GCTTATGAGCCGATCGACTT, downstream forward: _UP4_GATCCCTCGATGGAGTTAAT
  • BKK04730 (sigB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GCTTATGAGCCGATCGACTT, downstream forward: _UP4_GATCCCTCGATGGAGTTAAT

    • Labs working on this gene/protein

  • Bill Haldenwang, San Antonio, USA
  • Chet Price, Davis, USA homepage

    • References

    Reviews

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    Control of SigB activity by protein-protein interactions

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    Identification of the SigB regulon

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    Other publications

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