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rapA
response regulator aspartate phosphatase, dephosphorylates [protein|9896B99346B0D3F6D57F57377DB253B46135A37A|Spo0F]-P, control of the [SW|phosphorelay]
function
control of [SW|sporulation] initiation
product
response regulator aspartate phosphatase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.2|Response regulator aspartate phosphatase][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.5|Phosphatases controlling the phosphorelay][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.5|Phosphatases controlling the phosphorelay]Gene
Coordinates
1,315,869 1,317,005
The protein
Protein family
[SW|RAP family] (according to UniProt)[SW|Domains]
modular organization comprising an amino terminal alpha-helical domain connected to a domain formed by six [SW|TPR repeat|tetratrichopeptide repeats] [Pubmed|11923303,22267516]Structure
[PDB|4I9E] ([protein|1F860F4E66A3D503D5A97F17D4AB0504BEFE7F9D|RapF], 42% identity) [pubmed|23526880]Biological materials
Mutant
BKE12430 ([gene|25D89EF3C4D57B3E6F9AB0210029651F74356906|rapA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE12430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTAATCCCCCCTTTTGA, downstream forward: _UP4_CAAATCCAGAGAGGAGATTGBKK12430 ([gene|25D89EF3C4D57B3E6F9AB0210029651F74356906|rapA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK12430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTAATCCCCCCTTTTGA, downstream forward: _UP4_CAAATCCAGAGAGGAGATTGReferences
8643670,8730857,11923303,22267516,14651647,12618455,12107147,19380751,12850135,1378051,16091051,23569278,26582911,27122155,23526880,32132526 
