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murP
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murP

N-acetyl muramic acid permease of the phosphotransferase system, EIIBC of the PTS
Locus
BSU_01680
Isoelectric point
8.50
Molecular weight
47.44 kDa
Protein length
455 aa Sequence Blast
Gene length
1368 bp Sequence Blast
Function
N-acetyl muramic acid uptake and phosphorylation
Product
N-acetyl muramic acid PTS permease, EIIBC component
Essential
no
E.C.
2.7.1.69
Synonyms
ybbF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Cell wall degradation/ turnover → Utilization of cell wall components
  • Cellular processes → Transporters → Phosphotransferase system → Sugar specific PTS proteins
  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of amino sugars
  • Metabolism → Amino acid/ nitrogen metabolism → Utilization of nitrogen sources other than amino acids → Utilization of amino sugars
  • Groups of genes → Phosphoproteins → Phosphorylation on a Cys residue

    • Gene

    Coordinates
    189,790 191,157

    The protein

    Catalyzed reaction/ biological activity

  • transport and concomitant phosphorylation of N-acetyl muramic acid

    • Protein family

  • PTS permease, sucrose family PubMed

    • Paralogous protein(s)

  • BglP, SacX, SacP, TreP

    • Domains

  • PTS EIIB domain type-1 (aa 8-90) (according to UniProt)
  • PTS EIIC domain type-1 (aa 116-455) (according to UniProt)

    • Expression and Regulation

    Operons

    Genes
    murQ-murR-murP-amiE-nagZ-ybbC
    Description
    PubMed

    Regulatory mechanism

  • MurR: repression, PubMed, in MurR regulon

    • Regulation

  • expressed in late exponential and early stationary phase PubMed
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    Biological materials

    Mutant

  • MGNA-B950 (ybbF::erm), available at the NBRP B. subtilis, Japan
  • BKE01680 (murP::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTAAAACCCCTCCCCTTC, downstream forward: _UP4_TAAATTGTTTCTGTTTTAGG
  • BKK01680 (murP::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTAAAACCCCTCCCCTTC, downstream forward: _UP4_TAAATTGTTTCTGTTTTAGG

    • References

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