You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

metS

methionyl-tRNA synthetase

Locus

BSU_00380

Isoelectric point

4.96

Molecular weight

76.01 kDa

Protein length

664 aa Sequence Blast

Gene length

1995 bp Sequence Blast

Function

translation

Product

methionyl-tRNA synthetase

Essential

yes

E.C.

6.1.1.10

Synonyms

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

Hide small RNAs Zoom:

Categories containing this gene/protein

Information processing → Protein synthesis, modification and degradation → Translation → Aminoacyl-tRNA synthetases

Groups of genes → Essential genes

Groups of genes → Phosphoproteins → Phosphorylation on a Ser residue

Gene

Coordinates

45,633 → 47,627

Phenotypes of a mutant

essential PubMed

The protein

Catalyzed reaction/ biological activity

ATP + L-methionine + tRNA^Met --> AMP + diphosphate + L-methionyl-tRNA^Met (according to UniProt)

Protein family

Class-I aminoacyl-tRNA synthetase family (according to UniProt)

Domains

tRNA-binding domain (aa 570-662) (accordinig to UniProt)

Modification

phosphorylated on Ser-652 PubMed

Structure

1WE0 (from Thermus thermophilus hb8 mutant, 40% identity, 57% similarity) PubMed

Localization

cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

Genes

metS-yabD

Description

PubMed

Regulatory mechanism

Spo0A: repression, PubMed, in Spo0A regulon

Regulation

repressed under conditions that trigger sporulation (Spo0A) PubMed

Additional information

term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of metS PubMed

view in new tab