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licC

lichenan-specific permease of the phosphotransferase system, EIIC of the PTS

Locus

BSU_38580

Isoelectric point

8.58

Molecular weight

48.37 kDa

Protein length

452 aa Sequence Blast

Gene length

1359 bp Sequence Blast

Function

lichenan uptake and phosphorylation

Product

lichenan-specific lichenan-specific PTS, EIIC component

Essential

Synonyms

celB

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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Categories containing this gene/protein

Cellular processes → Transporters → Phosphotransferase system → Sugar specific PTS proteins

Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of other polymeric carbohydrates

Groups of genes → Membrane proteins

Gene

Coordinates

3,960,192 3,961,550

The protein

Protein family

PTS permease, lactose family PubMed

Paralogous protein(s)

YwbA, GmuC

Domains

PTS EIIC domain type-3 (aa 8-421) (according to UniProt)

Structure

3QNQ (EIIC component of diacetylchitobiose specific PTS from Bacillus cereus; 60% identity, 87% similarity) PubMed

Localization

cell membrane (according to UniProt)

Expression and Regulation

Operons

Genes

licB-licC-licA-licH

Description

PubMed

Sigma factors

SigA: sigma factor, PubMed, in SigA regulon

Regulatory mechanism

CcpA: repression, PubMed, in CcpA regulon

LicR: activation, PubMed, in LicR regulon

Regulation

carbon catabolite repression (CcpA) PubMed

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Biological materials

Mutant

BKE38580 (licC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACATAGCCCGCCCCTCTCT, downstream forward: _UP4_CTGTAGAGAAAGGAAGTGAA

BKK38580 (licC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACATAGCCCGCCCCTCTCT, downstream forward: _UP4_CTGTAGAGAAAGGAAGTGAA

References