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ldt
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ldt

L,D-transpeptidase involved in cell wall synthesis
Locus
BSU_14040
Isoelectric point
10.25
Molecular weight
17.59 kDa
Protein length
164 aa Sequence Blast
Gene length
495 bp Sequence Blast
Function
cell wall biosynthesis
Product
L,D-transpeptidase
Essential
no
Synonyms
ykuD
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Cell wall synthesis → Biosynthesis of peptidoglycan
  • Metabolism → Additional metabolic pathways → Biosynthesis of cell wall components → Biosynthesis of peptidoglycan
  • Lifestyles → Sporulation → Sporulation proteins → Spore coat proteins → Not yet assigned

    • Gene

    Coordinates
    1,476,518 1,477,012

    The protein

    Protein family

  • YkuD family (with YciB and YqjB, according to UniProt)

    • Paralogous protein(s)

  • YqjB

    • Domains

  • contains a N-terminal N-acetylglucosamine-polymer-binding LysM domain PubMed
  • LysM domain (aa 2-45) (according to UniProt)

    • Structure

  • 1Y7M PubMed
  • 2MTZ (complex with a peptidoglycan hexamuropeptide) PubMed

    • Localization

  • spore wall (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    ldt
    Description
    PubMed

    Sigma factors

  • SigK: sigma factor, PubMed, in SigK regulon

    • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon

    • Regulation

  • expressed during sporulation in the mother cell (SigK) PubMed
    • view in new tab

    Genes
    ykuE-ldt-ykuC
    Description
    PubMed

    Regulation

  • expressed during sporulation in the mother cell (SigK) PubMed
    • view in new tab

    Biological materials

    Mutant

  • MGNA-A766 (ykuD::erm), available at the NBRP B. subtilis, Japan
  • BKE14040 (ldt::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAGTTTCCTCATCCTCCTTT, downstream forward: _UP4_TAATGTTTTCTTATTTGTTT
  • BKK14040 (ldt::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAGTTTCCTCATCCTCCTTT, downstream forward: _UP4_TAATGTTTTCTTATTTGTTT

    • References

    Reviews

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    Original publications

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