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ggt
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ggt

gamma-glutamyltransferase
Locus
BSU_18410
Isoelectric point
5.45
Molecular weight
64.01 kDa
Protein length
587 aa Sequence Blast
Gene length
1764 bp Sequence Blast
Function
degradation of poly-glutamate capsules
Product
gamma-glutamyltransferase
Essential
no
E.C.
2.3.2.2
Synonyms
pac

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
2,004,677 2,006,440

The protein

Catalyzed reaction/ biological activity

  • α-amino acid + N-terminal (5-L-glutamyl)-[peptide] --> 5-L-glutamyl amino acid + N-terminal L-α-aminoacyl-[peptide] (according to UniProt)
  • glutathione + H2O --> L-cysteinylglycine + L-glutamate (according to UniProt)
  • S-substituted glutathione + H2O --> S-substitued L-cysteinylglycine + L-glutamate (according to UniProt)
  • Protein family

  • gamma-glutamyltransferase family (with YwrD, according to UniProt)
  • Structure

    Localization

  • extracellular (signal peptide) PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Regulation

  • strongly induced in response to glucose starvation in M9 medium PubMed
  • Additional information

  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed
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    Biological materials

    Mutant

  • BKE18410 (ggt::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTTCTCCCTCCTATATG, downstream forward: _UP4_TAAATAAAAAACTGTACTCG
  • BKK18410 (ggt::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTTCTCCCTCCTATATG, downstream forward: _UP4_TAAATAAAAAACTGTACTCG
  • References

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