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fliM
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fliM

flagellar motor switch protein, part of the basal body C-ring
Locus
BSU_16310
Isoelectric point
4.69
Molecular weight
37.37 kDa
Protein length
332 aa Sequence Blast
Gene length
999 bp Sequence Blast
Function
movement and chemotaxis
Product
flagellar motor switch protein
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Lifestyles → Exponential and early post-exponential lifestyles → Motility and chemotaxis → Flagellar proteins
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    1,701,684 1,702,682

    The protein

    Protein family

  • FliM family (single member, according to UniProt)

    • Paralogous protein(s)

  • FliY

    • Structure

  • 3SOH (central fragment, from Thermotoga maritima, 40% identity) PubMed

    • Localization

  • cell membrane (according to UniProt)
  • flagellum basal body (according to UniProt)
  • localizes as individual spots (puncta), this requires FliF PubMed

    • Expression and Regulation

    Operons

    Genes
    ylxF-fliK-flgD-flgE-swrD-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigD: sigma factor, PubMed, in SigD regulon

    • Regulatory mechanism

  • Spo0A: repression, in Spo0A regulon
  • CodY: repression, in CodY regulon
  • DegU: regulation, in DegU regulon
  • SwrA: activation, in SwrA regulon

    • Regulation

  • see fla-che operon
    • view in new tab

    Genes
    flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-swrD-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigD: sigma factor, PubMed, in SigD regulon

    • Regulatory mechanism

  • Spo0A: repression, in Spo0A regulon
  • SwrA: activation, in SwrA regulon
  • CodY: repression, in CodY regulon
  • DegU: repression, in DegU regulon

    • Regulation

  • expression during spore germination is strongly reduced under conditions of osmotic stress PubMed
    • view in new tab

    Biological materials

    Mutant

  • BKE16310 (fliM::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTCCTCACCTCCGTAT, downstream forward: _UP4_GATCACGACATAAGAGGTGA
  • BKK16310 (fliM::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTCCTCACCTCCGTAT, downstream forward: _UP4_GATCACGACATAAGAGGTGA

    • References

    Reviews

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    Original Publications

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