SubtiBank SubtiBank
exuR
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exuR

repression of the hexuronate utilization operon (uxaC-yjmB-yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA)
Locus
BSU_12370
Isoelectric point
5.85
Molecular weight
37.22 kDa
Protein length
333 aa Sequence Blast
Gene length
1002 bp Sequence Blast
Function
regulation of hexuronate utilization
Product
transcriptional repressor (LacI family)
Essential
no
Synonyms
yjmH
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of hexuronate
  • Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other
  • Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other

    • Gene

    Coordinates
    1,308,802 1,309,803

    The protein

    Protein family

  • LacI family

    • Domains

  • HTH lacI-type domain (aa 2-56) (according to UniProt)

    • Effectors of protein activity

  • galacturonate acts as the molecular inducer PubMed

    • Structure

  • 2HSG (CcpA, 32% identity) PubMed

    • Expression and Regulation

    Operons

    Genes
    yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigE: sigma factor, PubMed, in SigE regulon

    • Regulatory mechanism

  • ExuR: repression, in the absence of inducer, in ExuR regulon
  • CcpA: repression, PubMed PubMed, in CcpA regulon

    • Regulation

  • induced by galacturonate (ExuR) PubMed
    • view in new tab

    Genes
    uxaC-yjmB-yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • ExuR: repression, in the absence of inducer, in ExuR regulon
  • CcpA: repression, PubMed PubMed, in CcpA regulon

    • Regulation

  • induced by galacturonate (ExuR) PubMed
    • view in new tab

    Biological materials

    Mutant

  • MGNA-A372 (yjmH::erm), available at the NBRP B. subtilis, Japan
  • BKE12370 (exuR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTAATTCCCTTCCTTAT, downstream forward: _UP4_TGATGTCCCGTTTTTCAGCG
  • BKK12370 (exuR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTAATTCCCTTCCTTAT, downstream forward: _UP4_TGATGTCCCGTTTTTCAGCG

    • References

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