SubtiBank SubtiBank
vmlR
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

vmlR

F-type ATP-binding cassette protein, allosterically dissociates antibiotics (virginiamycin M, lincomycin) from their ribosomal binding sites
Locus
BSU_05610
Isoelectric point
6.73
Molecular weight
62.57 kDa
Protein length
547 aa Sequence Blast
Gene length
1644 bp Sequence Blast
Function
dissociation of antibiotics (virginiamycin M, lincomycin) from the ribosome
Product
ABCF ATPase
Essential
no
Synonyms
expZ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Lifestyles → Coping with stress → Resistance against toxins/ antibiotics

    • Gene

    Coordinates
    604,736 606,379

    The protein

    Protein family

  • ABC transporter superfamily (according to UniProt)
  • ABCF ATPase subfamily PubMed

    • Domains

  • 2 ABC transporter domains (aa 5-200, aa 292-504) (according to UniProt)

    • Structure

  • 6HA8 PubMed

    • Localization

  • cytoplasm PubMed

    • Expression and Regulation

    Operons

    Genes
    vmlR
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • RNA switch: , in RNA switch

    • Regulation

  • induced by virginiamycin M or lincomycin PubMed

    • Additional information

  • A ncRNA is predicted between 'vmlR' and 'ydgF' PubMed
    • view in new tab

    Biological materials

    Mutant

  • MGNA-C159 (expZ::erm), available at the NBRP B. subtilis, Japan
  • BKE05610 (vmlR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCCATATCCCTCGCTTTA, downstream forward: _UP4_TGAGGGAGAAAGTTCAAGCG
  • BKK05610 (vmlR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCCATATCCCTCGCTTTA, downstream forward: _UP4_TGAGGGAGAAAGTTCAAGCG

    • References

    Reviews

    Loading

    Original publications

    Loading