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dppC

dipeptide ABC transporter (permease)

Locus

BSU_12940

Isoelectric point

9.81

Molecular weight

35.65 kDa

Protein length

320 aa Sequence Blast

Gene length

963 bp Sequence Blast

Function

uptake of dipeptides

Product

dipeptide ABC transporter (permease)

Essential

Synonyms

dciAC

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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Categories containing this gene/protein

Cellular processes → Transporters → ABC transporters → Importers → Uptake of peptides

Metabolism → Amino acid/ nitrogen metabolism → Utilization of nitrogen sources other than amino acids → Utilization of peptides

Groups of genes → Membrane proteins

Gene

Coordinates

1,362,174 → 1,363,136

The protein

Protein family

Binding-protein-dependent transport system permease family (according to UniProt)

OppBC subfamily (according to UniProt)

Paralogous protein(s)

AppC, OppC

Domains

ABC transmembrane type-1 domain (aa 117-307) (according to UniProt)

Localization

cell membrane PubMed

Expression and Regulation

Operons

Genes

dppA-dppB-dppC-dppD-dppE

Description

PubMed

Sigma factors

SigA: sigma factor, PubMed, in SigA regulon

Regulatory mechanism

CodY: repression, PubMed, in CodY regulon

Regulation

repressed by glucose (2.9-fold) PubMed

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Genes

dppA-dppB-dppC-dppD-dppE-ykfA-ykfB-ykfC-ykfD

Description

PubMed

Regulatory mechanism

CodY: repression, PubMed, in CodY regulon

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Biological materials

Mutant

BKE12940 (ΔdppC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTGTACAGGGAGATTCACAC, downstream forward: _UP4_GACCCTAAGCTGAGGAGGTA

BKK12940 (ΔdppC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTGTACAGGGAGATTCACAC, downstream forward: _UP4_GACCCTAAGCTGAGGAGGTA

References