SubtiBank SubtiBank
aspS
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aspS

aspartyl-tRNA synthetase
Locus
BSU_27550
Isoelectric point
4.65
Molecular weight
65.80 kDa
Protein length
592 aa Sequence Blast
Gene length
1779 bp Sequence Blast
Function
translation
Product
aspartyl-tRNA synthetase
Essential
yes
E.C.
6.1.1.12
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Translation → Aminoacyl-tRNA synthetases
  • Groups of genes → Essential genes
  • Groups of genes → Phosphoproteins → Phosphorylation on either a Ser, Thr or Tyr residue

    • Gene

    Coordinates
    2,814,743 2,816,521

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • ATP + L-aspartate + tRNAAsx --> AMP + diphosphate + L-aspartyl-tRNAAsx (according to UniProt)

    • Protein family

  • Class-II aminoacyl-tRNA synthetase family (according to UniProt)

    • Modification

  • phosphorylated on ser/ thr/ tyr PubMed

    • Structure

  • 1EQR (from Escherichia coli, 52% identity, 68% similarity) PubMed

    • Additional information

  • belongs to the 100 most abundant proteins PubMed

    • Expression and Regulation

    Operons

    Genes
    hisS-aspS

    Regulatory mechanism

  • T-box: transcriptional antitermination, via tRNA controlled RNA switch, in T-box

    • Regulation

  • induced by histidine or aspartate limitation (T-box) PubMed
  • the T-box RNA is degraded by RNase Y PubMed
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    References

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