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bsrB
6S RNA, important for timing of [SW|sporulation]
function
antagonist of [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors][category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.1|6S RNA]Gene
Phenotypes of a mutant
increased [SW|biofilm formation] (in undomesticated strains) [pubmed|32862759]RNA
Catalyzed reaction/ biological activity
binds to [SW|RNA polymerase] in [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]-dependent manner to repress transcription from a subgroup of promoters [pubmed|16336121]Structure
[PDB|5VT0] (E. coli 6S RNA in complex with [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]-containing [SW|RNA polymerase] holoenzyme) [pubmed|28988932]The protein
Structure
[PDB|5VT0] (E. coli 6S RNA in complex with [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]-containing [SW|RNA polymerase] holoenzyme) [pubmed|28988932]Expression and Regulation
Operons
genes
[gene|E85341621B3835F63F07C506E08B73A92E588B1F|bsrB]
description
[Pubmed|22383849]
genes
[gene|E85341621B3835F63F07C506E08B73A92E588B1F|bsrB]-[gene|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|recQ]-[gene|BEBA71A2EF56DAEAF80924856DA68124805BB158|yocH]
description
[Pubmed|22383849]
References
Reviews
17714443,16336121,24786589,29916345 Research papers
21881410,24464747,25483037,25576829,26873600,28988932,32862759 
