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fadA
acetyl-CoA C-acyltransferase
function
fatty acid degradation
product
acetyl-CoA C-acyltransferase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.1|Utilization of lipids] → [category|SW 2.4.1.3|Utilization of fatty acids]Gene
Coordinates
3,368,839 3,370,014
The protein
Catalyzed reaction/ biological activity
acetyl-CoA + acyl-CoA --> 3-oxoacyl-CoA + CoA (according to UniProt)Protein family
[SW|thiolase-like superfamily] (according to UniProt)Paralogous protein(s)
[protein|226100C0AC13BB345DB0F0F309DEB7F91F3770B0|MmgA], [protein|CF6B79564DBED3C6CAF64D01BD01D2A03675F16F|YhfS] Structure
[PDB|3SS6] (the protein of ''B. anthracis'', 41% identity, 73% similarity)Biological materials
Mutant
MGNA-A603 (yusK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/603 NBRP B. subtilis, Japan]BKE32830 ([gene|07498A0A3CB598A6E388540124A4F56E781C86FA|fadA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE32830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GACTGCCTCTTTCATAAGCT, downstream forward: _UP4_TTATGCTAAAGGGGGAAAAABKK32830 ([gene|07498A0A3CB598A6E388540124A4F56E781C86FA|fadA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK32830 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GACTGCCTCTTTCATAAGCT, downstream forward: _UP4_TTATGCTAAAGGGGGAAAAAReferences
17189250,12817086,17919287