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aroH

chorismate mutase (isozymes 1 and 2)

locus

BSU_22690

5.52

14.38 kDa

protein length

127 aa Sequence Blast

gene length

384 bp Sequence Blast

function

biosynthesis of aromatic amino acids

product

chorismate mutase (isozymes 1 and 2)

essential

5.4.99.5

synonyms

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.13|Biosynthesis/ acquisition of aromatic amino acids]

Gene

Coordinates

2,377,632 2,378,015

The protein

Catalyzed reaction/ biological activity

Chorismate --> prephenate (according to UniProt)

[SW|Domains]

Chorismate mutase aroH-type domain (aa 3-121) (according to UniProt)

Structure

[PDB|2CHT] (complex with a transition state analog) [pubmed|8378335]

[PDB|1DBF]

Expression and Regulation

Operons

genes

description

[pubmed|22383849]

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genes

description

[pubmed|21815947]

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Biological materials

Mutant

BKE22690 ([gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCTCCGCGAATTCCGCGAA, downstream forward: _UP4_TAATACGATAAGAACAGCTT

BKK22690 ([gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGCTCCGCGAATTCCGCGAA, downstream forward: _UP4_TAATACGATAAGAACAGCTT

References

Reviews

12698486,9383421,12966138

Original publications

8378335,25422475,12630863,10960481,2105742,8643526,26278727,26641683,21243152,15034619,14709097,21815947,28743924