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yitD
phosphosulfolactate synthase
function
biosynthesis of L-sulfolactate
product
phosphosulfolactate synthase
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]Gene
Coordinates
1,173,333 1,174,091
The protein
Catalyzed reaction/ biological activity
(2R)-O-phospho-3-sulfolactate --> H+ + phosphoenolpyruvate + sulfite (according to UniProt)Protein family
phosphosulfolactate synthase family (single member, according to UniProt)Structure
[PDB|1U83]Expression and Regulation
Operons
genes
[gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]-[gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]
description
[Pubmed|22383849]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15383836], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon][protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|15699190,15383836], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]regulation
expressed during [SW|sporulation] in the mother cell ([protein|search|SigE], [protein|search|SigK]) [Pubmed|15699190,15383836]view in new tabBiological materials
Mutant
MGNA-B178 (yitD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1177 NBRP B. subtilis, Japan]BKE10950 ([gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10950 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGGCAATTCTAGTGAAAAAT, downstream forward: _UP4_TAAAATAGCGGCTGCGGGGCBKK10950 ([gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10950 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGGCAATTCTAGTGAAAAAT, downstream forward: _UP4_TAAAATAGCGGCTGCGGGGCReferences
