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20th International Conference on Bacilli and Gram-Positive Bacteria. Washington, D.C. July 23-26, 2019.
Category: Resistance against oxidative and electrophile stress
4.3.8. Resistance against oxidative and electrophile stress
| Name | Function |
| aag | DNA repair, survival of stress conditions |
| adhA | response to toxic formaldehyde |
| adhR | regulation of the protective response to formaldehyde and methylglyoxal |
| ahpC | resistance against peroxide stres |
| ahpF | resistance against peroxide stress |
| ahpT | protection of proteins against oxidative damage |
| aldY | stress resistance |
| azoR1 | quinone detoxification |
| azoR2 | resistance to 2-methylhydroquinone |
| brxA | de-bacillithiolation of S-bacillithiolated [protein|7A3A8AF7728474204396BB7A548F747D28E6FAC7|OhrR] and [protein|23F405D5B849E4EDC1D599F86C71DFD2E55C0305|MetE] |
| brxB | de-bacillithiolation of S-bacillithiolated [protein|7A3A8AF7728474204396BB7A548F747D28E6FAC7|OhrR] and [protein|23F405D5B849E4EDC1D599F86C71DFD2E55C0305|MetE] |
| bsaA | unknown |
| bshA | biosynthesis of bacillithiol |
| bshB1 | biosynthesis of bacillithiol |
| bshB2 | biosynthesis of bacillithiol |
| bshC | biosynthesis of bacillithiol |
| bstA | detoxification |
| catD | detoxification of catechol |
| catE | detoxification of catechol |
| catR | resistance against oxidative and electrophile stress |
| csbA | protection against paraquat stress |
| csbB | lipoteichoic acid glycosylation , survival of stress conditions |
| csbC | protection against paraquat stress |
| cypC | biosynthesis of beta-hydroxy fatty acid for lipopeptides |
| dps | iron storage, survival of of stress conditions |
| efeB | ferrous iron conversion |
| glxA | detoxification of methylglyoxal |
| glxB | detoxification of methylglyoxal |
| guaD | deamination of guanine to xanthine, purine salvage and interconversion |
| hpf | dimerization of ribosomes in the stationary phase, protection against paraquat stress |
| hxlA | ribulose monophosphate pathway for formaldehyde fixation |
| hxlB | ribulose monophosphate pathway for formaldehyde fixation |
| hxlR | regulation of the ribulose monophosphate pathway |
| hypO | protection against NaOCl stress |
| hypR | control of the nitroreductase gene [gene|9DF5999568760E016ECA988385A1FA61A257D486|hypO] in response to disulfide stress (diamide, NaOCl) |
| katA | detoxification (degradation) of hydrogen peroxide |
| katE | detoxification (degradation) of hydrogen peroxide |
| katX | detoxification (degradation) of hydrogen peroxide |
| liaF | control of [protein|49E70A20CC05DBE485953C0AE34E634EFB33C3B2|LiaR] activity |
| liaG | unknown |
| liaH | resistance against oxidative stress and cell wall antibiotics |
| liaI | resistance against oxidative stress and cell wall antibiotics |
| liaR | regulation of the [gene|B6D1159454969D1D578E05D5CE2259E079688510|liaI]-[gene|AE4BF12C368468C553EED7A696D5EFC63F56CA39|liaH]-[gene|A71B0392FFF70EFFC096E7E9BD5FE30792821CDD|liaG]-[gene|C107A958DFA2B0DA4837E2F9F648CD329A3116AC|liaF]-[gene|9A1871BD853254EEA8B4E78CA187F9315CBDF43D|liaS]-[gene|search|liaR ]operon |
| liaS | control of [protein|49E70A20CC05DBE485953C0AE34E634EFB33C3B2|LiaR] activity in response to bacitracin |
| mgsR | controls a subset of general stress genes |
| mhqA | resistence to methyl-hydroxyquinone |
| mhqD | may be involved in protection against methyl-hydroquinone |
| mhqE | resistance to methyl hydroquinone and catechol |
| mhqN | unknown |
| mhqO | resistence to methyl-hydroxyquinone |
| mhqP | may be involved in protection against methyl-hydroquinone |
| mhqR | regulation of resistance to quinones and diamide |
| mrgA | iron storage, |
| msrA | regeneration of methionine and restoration of protein function after oxidative damage |
| msrB | regeneration of methionine and restoration of protein function after oxidative damage |
| nfrA | unknown |
| ohrA | organic peroxide resistance |
| ohrB | organic peroxide resistance |
| ohrR | regulation of [gene|869E46AECF6249610F8541E403D834284B62171D|ohrA] expression in response to organic peroxides |
| perR | regulation of the response to peroxide |
| rnr | nonspecific degradation of rRNA |
| sodA | detoxification of oxygen radicals |
| sodF | detoxification of oxygen radicals |
| spx | negative and positive regulator of many genes |
| sqhC | biosynthesis of sporulenes |
| tpx | unknown |
| trxA | protection of proteins against oxidative damage |
| trxB | keeps [protein|4E5C84FDC8FE2FEFF47306C91ECAB7F17D3E38E9|thioredoxin] in the reduced state |
| tsaE | control of tRNA modification |
| ydaG | survival of stress conditions |
| ydeA | detoxification of methylglyoxal |
| ydhK | survival of stress conditions |
| yerD | protection against paraquat stress |
| yfhE | survival of stress conditions and low temperatures |
| yfkH | survival of stress conditions |
| yfkI | protection against paraquat stress |
| yfkJ | survival of stress conditions |
| yfkM | detoxification of methylglyoxal |
| yfkS | germination, survival of of stress conditions |
| yflA | protection against paraquat stress |
| yhdN | detoxification of methylglyoxal |
| yitT | protection against paraquat stress |
| yjbC | survival of paraquat stress |
| yjgD | survival of stress conditions |
| ylxP | protection against paraquat stress |
| ymaD | protection against oxidative stress |
| yodB | regulation of quinone and diamide detoxification |
| yodC | regeneration of NAD from NADH |
| yojM | unknown |
| ypdA | recycling of oxidized bacillithiol disulfide to the reduced form (BSH) |
| yqhB | protection against stress conditions |
| yqjL | resistence against paraquat |
| yqjM | reduction of double bonds of nonsaturated aldehydes |
| yraA | detoxification of methylglyoxal |
| ytpQ | maybe involved in iron homeostasis |
| yugU | survival of stress conditions |
| yvgN | unknown |
| ywiE | phospholipiid biosynthesis, protection against paraquat stress |
| yxiS | survival of stress conditions |
| yxjJ | survival of stress conditions |
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