The second international online conference #Subtillery2021 will be held 14th - 18th June - save the date, for more information see the conference website!
The 21st International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
The 21st International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
Category: Resistance against oxidative and electrophile stress
4.3.8. Resistance against oxidative and electrophile stress
Name | Function |
aag | DNA repair, survival of stress conditions |
adhA | response to toxic formaldehyde |
adhR | regulation of the protective response to formaldehyde and methylglyoxal |
ahpC | resistance against peroxide stres |
ahpF | resistance against peroxide stress |
ahpT | protection of proteins against oxidative damage |
aldY | stress resistance |
azoR1 | quinone detoxification |
azoR2 | resistance to 2-methylhydroquinone |
brxA | de-bacillithiolation of S-bacillithiolated [protein|7A3A8AF7728474204396BB7A548F747D28E6FAC7|OhrR] and [protein|23F405D5B849E4EDC1D599F86C71DFD2E55C0305|MetE] |
brxB | de-bacillithiolation of S-bacillithiolated [protein|7A3A8AF7728474204396BB7A548F747D28E6FAC7|OhrR] and [protein|23F405D5B849E4EDC1D599F86C71DFD2E55C0305|MetE] |
bsaA | unknown |
bshA | biosynthesis of bacillithiol |
bshB1 | biosynthesis of bacillithiol |
bshB2 | biosynthesis of bacillithiol |
bshC | biosynthesis of bacillithiol |
bstA | detoxification |
catD | detoxification of catechol |
catE | detoxification of catechol |
catR | resistance against oxidative and electrophile stress |
csbA | protection against paraquat stress |
csbB | lipoteichoic acid glycosylation , survival of stress conditions |
csbC | protection against paraquat stress |
cypC | biosynthesis of beta-hydroxy fatty acid for lipopeptides |
dps | iron storage, survival of of stress conditions |
efeB | ferrous iron conversion |
glxA | detoxification of methylglyoxal |
glxB | detoxification of methylglyoxal |
guaD | deamination of guanine to xanthine, purine salvage and interconversion |
hpf | protection of essential ribosomal proteins ([protein|F1969E4C7BAAF70BCBE570F58350C12A3E417539|S2] and [protein|E7F4E01A6005C8469EAC64E8DFED96D0F29791A9|S3]) |
hxlA | ribulose monophosphate pathway for formaldehyde fixation |
hxlB | ribulose monophosphate pathway for formaldehyde fixation |
hxlR | regulation of the ribulose monophosphate pathway |
hypO | protection against NaOCl stress |
hypR | control of the nitroreductase gene [gene|9DF5999568760E016ECA988385A1FA61A257D486|hypO] in response to disulfide stress (diamide, NaOCl) |
katA | detoxification (degradation) of hydrogen peroxide |
katE | detoxification (degradation) of hydrogen peroxide |
katX | detoxification (degradation) of hydrogen peroxide |
liaF | control of [protein|49E70A20CC05DBE485953C0AE34E634EFB33C3B2|LiaR] activity |
liaG | unknown |
liaH | resistance against oxidative stress and cell wall antibiotics, [SW|protein secretion] |
liaI | resistance against oxidative stress and cell wall antibiotics |
liaR | regulation of the [gene|B6D1159454969D1D578E05D5CE2259E079688510|liaI]-[gene|AE4BF12C368468C553EED7A696D5EFC63F56CA39|liaH]-[gene|A71B0392FFF70EFFC096E7E9BD5FE30792821CDD|liaG]-[gene|C107A958DFA2B0DA4837E2F9F648CD329A3116AC|liaF]-[gene|9A1871BD853254EEA8B4E78CA187F9315CBDF43D|liaS]-[gene|search|liaR ]operon |
liaS | control of [protein|49E70A20CC05DBE485953C0AE34E634EFB33C3B2|LiaR] activity in response to bacitracin |
mgsR | controls a subset of general stress genes |
mhqA | resistence to methyl-hydroxyquinone |
mhqD | may be involved in protection against methyl-hydroquinone |
mhqE | resistance to methyl hydroquinone and catechol |
mhqN | unknown |
mhqO | resistence to methyl-hydroxyquinone |
mhqP | may be involved in protection against methyl-hydroquinone |
mhqR | regulation of resistance to quinones and diamide |
mrgA | iron storage, |
msrA | regeneration of methionine and restoration of protein function after oxidative damage |
msrB | regeneration of methionine and restoration of protein function after oxidative damage |
nfrA | unknown |
ohrA | organic peroxide resistance |
ohrB | organic peroxide resistance |
ohrR | regulation of [gene|869E46AECF6249610F8541E403D834284B62171D|ohrA] expression in response to organic peroxides |
perR | regulation of the response to peroxide |
rnr | nonspecific degradation of rRNA |
sodA | detoxification of oxygen radicals |
sodF | detoxification of oxygen radicals |
spx | negative and positive regulator of many genes |
sqhC | biosynthesis of sporulenes |
tpx | unknown |
trxA | protection of proteins against oxidative damage |
trxB | keeps [protein|4E5C84FDC8FE2FEFF47306C91ECAB7F17D3E38E9|thioredoxin] in the reduced state |
tsaE | control of tRNA modification |
ydaG | survival of stress conditions |
ydeA | detoxification of methylglyoxal |
ydhK | survival of stress conditions |
yerD | protection against paraquat stress |
yfhE | survival of stress conditions and low temperatures |
yfkH | survival of stress conditions |
yfkI | protection against paraquat stress |
yfkJ | survival of stress conditions |
yfkM | detoxification of methylglyoxal |
yfkS | germination, survival of of stress conditions |
yflA | protection against paraquat stress |
yhdA | protection against oxidative stress |
yhdN | detoxification of methylglyoxal |
yitT | protection against paraquat stress |
yjbC | survival of paraquat stress |
yjgD | survival of stress conditions |
ylxP | protection against paraquat stress |
ymaD | protection against oxidative stress |
yodB | regulation of quinone and diamide detoxification |
yodC | regeneration of NAD from NADH |
yojM | unknown |
ypdA | recycling of oxidized bacillithiol disulfide to the reduced form (BSH) |
yqhB | protection against stress conditions |
yqjL | resistence against paraquat |
yqjM | reduction of double bonds of nonsaturated aldehydes |
yraA | detoxification of methylglyoxal |
ytpQ | maybe involved in iron homeostasis |
yugU | survival of stress conditions |
yvgN | unknown |
ywiE | phospholipiid biosynthesis, protection against paraquat stress |
yxiS | survival of stress conditions |
yxjJ | survival of stress conditions |
important original publications
reviews