SubtiBank SubtiBank
Category: Biosynthesis/ acquisition of nucleotides
An ordered knock out library of all non-essential genes in B. subtilis is now available at Addgene. Information on ordering a copy can be found here. See Koo et al. 2017 for details about library construction.

Category: Biosynthesis/ acquisition of nucleotides

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2. Metabolism

2.5. Nucleotide metabolism

2.5.2. Biosynthesis/ acquisition of nucleotides

2.5.2.1. Biosynthesis/ acquisition of purine nucleotides

NameFunction
adkADP formation
gmkGTP biosynthesis
guaAbiosynthesis of GMP
guaBbiosynthesis of GMP
nupGpurine uptake
nupNuptake of guanosine
nupOuptake of guanosine
nupPuptake of guanosine
nupQuptake of guanosine
pbuGhypoxanthine and guanine uptake
pbuXxanthine uptake
prsphosphoribosylpyrophosphate synthesis (biosynthesis of histidine)
purApurine biosynthesis
purBpurine biosynthesis
purCpurine biosynthesis
purDpurine biosynthesis
purEpurine biosynthesis
purFpurine biosynthesis
purHpurine biosynthesis
purKpurine biosynthesis
purLpurine biosynthesis
purMpurine biosynthesis
purNpurine biosynthesis
purQpurine biosynthesis
purRregulation of purine biosynthesis
purSpurine biosynthesis
purTpurine biosynthesis
ykkEpurine nucleotide synthesis

2.5.2.2. Biosynthesis/ acquisition of purine nucleotides/ based on similarity

NameFunction
pbuOunknown

2.5.2.3. Purine salvage and interconversion

NameFunction
aptpurine salvage and interconversion
dckpurine salvage and interconversion
deoDpurine salvage and interconversion
dgkpurine salvage and interconversion
guaCpurine salvage and interconversion
guaDdeamination of guanine to xanthine, purine salvage and interconversion
hprTpurine salvage and interconversion, control of ftsH expression
pupGpurine salvage and interconversion
xptpurine salvage and interconversion

2.5.2.4. Biosynthesis/ acquisition of pyrimidine nucleotides

NameFunction
cmksynthesis of CTP and dCTP
prsphosphoribosylpyrophosphate synthesis (biosynthesis of histidine)
pyrAApyrimidine biosynthesis
pyrABpyrimidine biosynthesis
pyrBpyrimidine biosynthesis
pyrCpyrimidine biosynthesis
pyrDpyrimidine biosynthesis
pyrEpyrimidine biosynthesis
pyrFpyrimidine biosynthesis
pyrGpyrimidine biosynthesis
pyrHpyrimidine biosynthesis
pyrKpyrimidine biosynthesis
pyrPuracil transport in/out via proton symport
pyrRregulation of pyrimidine biosynthesis
tdkbiosynthesis of thymidine nucleotides
thyAbiosynthesis of thymidine nucleotides
thyBbiosynthesis of thymidine nucleotides
tmkTTP biosynthesis
udkUMP synthesis
uppUMP synthesis

2.5.2.5. Biosynthesis/ acquisition of nucleotides/ other

NameFunction
nrdEsynthesis of deoxyribonucleoside triphosphates
nrdEBunknown
nrdFsynthesis of deoxyribonucleoside triphosphates
nrdIsynthesis of deoxyribonucleoside triphosphates
rnrnonspecific degradation of rRNA
yhcRutilization of nucleic acids

2.5.2.6. Biosynthesis/ acquisition of nucleotides/ other/ based on similarity

NameFunction
yutKunknown
yxlAunknown