The second international online conference #Subtillery2021 will be held 14th - 18th June - save the date, for more information see the conference website!
The 21st International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
The 21st International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
Category: Cell wall synthesis
1.1. Cell envelope and cell division
1.1.1.1. Biosynthesis of peptidoglycan
| Name | Function |
| alr | peptidoglycan biosynthesis |
| amj | export of lipid II |
| asd | biosynthesis of threonine, lysine, dipicolic acid, peptidoglycan |
| dapA | biosynthesis of lysine and peptidoglycan |
| dapB | biosynthesis of lysine and peptidoglycan |
| dapF | biosynthesis of lysine and peptidoglycan |
| dapG | biosynthesis of lysine and peptidoglycan |
| dat | peptidoglycan precursor biosynthesis |
| ddl | peptidoglycan precursor biosynthesis |
| gcaD | cell wall metabolism |
| glmM | cell wall synthesis |
| glmR | regulation of carbon partitioning between central metabolism and peptidoglycan biosynthesis, localization of [protein|A8EEC896B279CFDDE9C3A6F146A04EC822E33A4F|PBP1] |
| glmS | cell wall synthesis |
| ldcB | cell wall synthesis |
| ldt | cell wall biosynthesis |
| mraY | peptidoglycan precursor biosynthesis |
| murAA | peptidoglycan precursor biosynthesis |
| murAB | peptidoglycan precursor biosynthesis |
| murB | peptidoglycan precursor biosynthesis |
| murC | peptidoglycan precursor biosynthesis |
| murD | peptidoglycan precursor biosynthesis |
| murE | peptidoglycan precursor biosynthesis |
| murF | peptidoglycan precursor biosynthesis |
| murG | peptidoglycan precursor biosynthesis |
| murJ | export of lipid II |
| patA | biosynthesis of lysine and peptidoglycan |
| pgcA | interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate |
| racE | peptidoglycan precursor biosynthesis |
| spoVB | spore cortex peptidoglycan synthesis |
| spoVE | spore cortex peptidoglycan synthesis |
| walJ | coordination of cell division with DNA replication |
| yabM | alternate pathway for peptidoglycan strand synthesis |
| yciB | unknown |
| ykuQ | biosynthesis of lysine and peptidoglycan |
| ykuR | biosynthesis of lysine and peptidoglycan |
| ylmD | quality control to maintain composition and integrity of peptidoglycan |
| yrpC | peptidoglycan precursor biosynthesis |
important publications
1.1.1.2. Autolytic activity required for peptidoglycan synthesis (cell elongation)
| Name | Function |
| cwlO | cell wall synthesis, cell elongation |
| ftsE | control of [SW|cell wall synthesis] |
| ftsX | control of cell wall synthesis |
| lytE | major autolysin, cell elongation and separation |
1.1.1.3. Biosynthesis of lipoteichoic acid
| Name | Function |
| csbB | lipoteichoic acid glycosylation , survival of stress conditions |
| dgkA | cell wall biosynthesis |
| dgkB | biosynthesis of lipoteichoic acid |
| ltaS | biosynthesis of lipoteichoic acid |
| yfhO | lipoteichoic acid glycosylation |
| yfnI | biosynthesis of lipoteichoic acid |
| yqgS | biosynthesis of lipoteichoic acid |
| yvgJ | biosynthesis of lipoteichoic acid |
1.1.1.4. Biosynthesis of teichoic acid
| Name | Function |
| dltA | biosynthesis of teichoic acid |
| dltB | biosynthesis of teichoic acid |
| dltC | biosynthesis of teichoic acid |
| dltD | biosynthesis of teichoic acid |
| dltE | biosynthesis of teichoic acid |
| ggaA | biosynthesis of teichoic acid |
| ggaB | biosynthesis of teichoic acid |
| gtaB | biosynthesis of teichoic acid |
| gtcA | biosynthesis of teichoic acids |
| mnaA | biosynthesis of teichoic acid |
| pgcA | interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate |
| tagA | biosynthesis of teichoic acid |
| tagB | biosynthesis of teichoic acid |
| tagC | biosynthesis of teichoic acid |
| tagD | biosynthesis of teichoic acid |
| tagE | biosynthesis of teichoic acid |
| tagF | biosynthesis of teichoic acid |
| tagG | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
| tagH | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
| tagO | biosynthesis of teichoic acid |
1.1.1.5. Biosynthesis of teichuronic acid
| Name | Function |
| tuaA/1 | biosynthesis of teichuronic acid |
| tuaA/2 | biosynthesis of teichuronic acid |
| tuaB | biosynthesis of teichuronic acid |
| tuaC | biosynthesis of teichuronic acid |
| tuaD | biosynthesis of teichuronic acid |
| tuaE | biosynthesis of teichuronic acid |
| tuaF | biosynthesis of teichuronic acid |
| tuaG | biosynthesis of teichuronic acid |
| tuaH | biosynthesis of teichuronic acid |
1.1.1.6. Export of anionic polymers and attachment to peptidoglycan
| Name | Function |
| tagG | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
| tagH | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
| tagT | transfer of anionic cell wall polymers from lipid-linked precursors to peptidoglycan |
| tagU | transfer of anionic cell wall polymers from lipid-linked precursors to peptidoglycan |
| tagV | transfer of anionic cell wall polymers from lipid-linked precursors to peptidoglycan |
1.1.1.7. Penicillin-binding proteins
| Name | Function |
| dacA | carboxypeptidase |
| dacB | control of peptide cross-linking in spore peptidoglycan |
| dacC | carboxypeptidase |
| dacF | control of peptide cross-linking in spore peptidoglycan |
| pbpA | formation of a rod-shaped peptidoglycan cell wall, spore outgrowth |
| pbpB | septation, [SW|cell division] |
| pbpC | unknown |
| pbpD | bifunctional glucosyltransferase/ transpeptidase |
| pbpE | endopeptidase |
| pbpF | bifunctional glucosyltransferase/ transpeptidase, synthesis of spore peptidoglycan |
| pbpG | bifunctional glucosyltransferase/ transpeptidase, synthesis of spore peptidoglycan |
| pbpH | formation of a rod-shaped peptidoglycan cell wall |
| pbpI | unknown |
| pbpX | endopeptidase |
| ponA | bifunctional glucosyltransferase/ transpeptidase, polymerizes and cross-links peptidoglycan |
| spoVD | synthesis of spore peptidoglycan |
Reviews
Important publications
1.1.1.8. Biosynthesis of the carrier lipid undecaprenylphosphate
| Name | Function |
| bcrC | cell wall synthesis, resistance to bacitracin and oxidative stress |
| uppS | cell wall biosynthesis |
important original publication
important reviews