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21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.
Category: Cell wall synthesis
1.1. Cell envelope and cell division
1.1.1.1. Biosynthesis of peptidoglycan
| Name | Function |
| alr | peptidoglycan biosynthesis |
| amj | export of lipid II |
| asd | biosynthesis of threonine, lysine, dipicolic acid, peptidoglycan |
| dapA | biosynthesis of lysine and peptidoglycan |
| dapB | biosynthesis of lysine and peptidoglycan |
| dapF | biosynthesis of lysine and peptidoglycan |
| dapG | biosynthesis of lysine and peptidoglycan |
| dat | peptidoglycan precursor biosynthesis |
| ddl | peptidoglycan precursor biosynthesis |
| gcaD | cell wall metabolism |
| glmM | cell wall synthesis |
| glmR | regulation of carbon partitioning between central metabolism and peptidoglycan biosynthesis, localization of [protein|A8EEC896B279CFDDE9C3A6F146A04EC822E33A4F|PBP1] |
| glmS | cell wall synthesis |
| ldcB | cell wall synthesis |
| ldt | cell wall biosynthesis |
| mraY | peptidoglycan precursor biosynthesis |
| murAA | peptidoglycan precursor biosynthesis |
| murAB | peptidoglycan precursor biosynthesis |
| murB | peptidoglycan precursor biosynthesis |
| murC | peptidoglycan precursor biosynthesis |
| murD | peptidoglycan precursor biosynthesis |
| murE | peptidoglycan precursor biosynthesis |
| murF | peptidoglycan precursor biosynthesis |
| murG | peptidoglycan precursor biosynthesis |
| murJ | export of lipid II |
| patA | biosynthesis of lysine and peptidoglycan |
| pgcA | interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate |
| racE | peptidoglycan precursor biosynthesis |
| spoVB | spore cortex peptidoglycan synthesis |
| spoVE | spore cortex peptidoglycan synthesis |
| walJ | coordination of cell division with DNA replication |
| yabM | alternate pathway for peptidoglycan strand synthesis |
| yciB | unknown |
| ykuQ | biosynthesis of lysine and peptidoglycan |
| ykuR | biosynthesis of lysine and peptidoglycan |
| ylmD | quality control to maintain composition and integrity of peptidoglycan |
| yrpC | peptidoglycan precursor biosynthesis |
important publications
1.1.1.2. Autolytic activity required for peptidoglycan synthesis (cell elongation)
| Name | Function |
| cwlO | cell wall synthesis, cell elongation |
| ftsE | control of [SW|cell wall synthesis] |
| ftsX | control of cell wall synthesis |
| lytE | major autolysin, cell elongation and separation |
1.1.1.3. Biosynthesis of lipoteichoic acid
| Name | Function |
| csbB | lipoteichoic acid glycosylation , survival of stress conditions |
| dgkA | cell wall biosynthesis |
| dgkB | biosynthesis of lipoteichoic acid |
| ltaS | biosynthesis of lipoteichoic acid |
| yfhO | lipoteichoic acid glycosylation |
| yfnI | biosynthesis of lipoteichoic acid |
| yqgS | biosynthesis of lipoteichoic acid |
| yvgJ | biosynthesis of lipoteichoic acid |
1.1.1.4. Biosynthesis of teichoic acid
| Name | Function |
| dltA | biosynthesis of teichoic acid |
| dltB | biosynthesis of teichoic acid |
| dltC | biosynthesis of teichoic acid |
| dltD | biosynthesis of teichoic acid |
| dltE | biosynthesis of teichoic acid |
| ggaA | biosynthesis of teichoic acid |
| ggaB | biosynthesis of teichoic acid |
| gtaB | biosynthesis of teichoic acid |
| gtcA | biosynthesis of teichoic acids |
| mnaA | biosynthesis of teichoic acid |
| pgcA | interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate |
| tagA | biosynthesis of teichoic acid |
| tagB | biosynthesis of teichoic acid |
| tagC | biosynthesis of teichoic acid |
| tagD | biosynthesis of teichoic acid |
| tagE | biosynthesis of teichoic acid |
| tagF | biosynthesis of teichoic acid |
| tagG | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
| tagH | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
| tagO | biosynthesis of teichoic acid |
1.1.1.5. Biosynthesis of teichuronic acid
| Name | Function |
| tuaA/1 | biosynthesis of teichuronic acid |
| tuaA/2 | biosynthesis of teichuronic acid |
| tuaB | biosynthesis of teichuronic acid |
| tuaC | biosynthesis of teichuronic acid |
| tuaD | biosynthesis of teichuronic acid |
| tuaE | biosynthesis of teichuronic acid |
| tuaF | biosynthesis of teichuronic acid |
| tuaG | biosynthesis of teichuronic acid |
| tuaH | biosynthesis of teichuronic acid |
1.1.1.6. Export of anionic polymers and attachment to peptidoglycan
| Name | Function |
| tagG | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
| tagH | [category|SW 2.6.1.3|Biosynthesis of teichoic acid] |
| tagT | transfer of anionic cell wall polymers from lipid-linked precursors to peptidoglycan |
| tagU | transfer of anionic cell wall polymers from lipid-linked precursors to peptidoglycan |
| tagV | transfer of anionic cell wall polymers from lipid-linked precursors to peptidoglycan |
1.1.1.7. Penicillin-binding proteins
| Name | Function |
| dacA | carboxypeptidase |
| dacB | control of peptide cross-linking in spore peptidoglycan |
| dacC | carboxypeptidase |
| dacF | control of peptide cross-linking in spore peptidoglycan |
| pbpA | formation of a rod-shaped peptidoglycan cell wall, spore outgrowth |
| pbpB | septation, [SW|cell division] |
| pbpC | unknown |
| pbpD | bifunctional glucosyltransferase/ transpeptidase |
| pbpE | endopeptidase |
| pbpF | bifunctional glucosyltransferase/ transpeptidase, synthesis of spore peptidoglycan |
| pbpG | bifunctional glucosyltransferase/ transpeptidase, synthesis of spore peptidoglycan |
| pbpH | formation of a rod-shaped peptidoglycan cell wall |
| pbpI | unknown |
| pbpX | endopeptidase |
| ponA | bifunctional glucosyltransferase/ transpeptidase, polymerizes and cross-links peptidoglycan |
| spoVD | synthesis of spore peptidoglycan |
Reviews
Important publications
1.1.1.8. Biosynthesis of the carrier lipid undecaprenylphosphate
| Name | Function |
| bcrC | cell wall synthesis, resistance to bacitracin and oxidative stress |
| uppS | cell wall biosynthesis |
important original publication
important reviews