yxkC
168
unknown
locus
BSU_38850
Molecular weight
22.00 kDa
pI
9.292
function
unknown
product
unknown
essential
no
synonyms
yxkC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
3,989,232 3,989,873
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The protein
[wiki|Domains]
[wiki|DUF4352] (aa 46 ... 175)(according to UniProt)
Structure
[PDB|4LES] (from B. anthracis, corresponds to aa 79 ... 213, 30% identity)
[AF|P94356]
[wiki|Localization]
extracellular (signal peptide) [Pubmed|18957862]
membrane [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]
description
[Pubmed|10746760]
regulation
repressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|12823818]
regulatory mechanism
[protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA]: activation, [Pubmed|12823818], in [regulon|protein:857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA regulon]
sigma factors
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|15033535], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
Biological materials
Mutant
MGNA-B737 (yxkC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1736 NBRP B. subtilis, Japan]
BKE38850 (''[gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]''::''erm'', available in the BGSC and in [wiki|Jörg Stülke]'s lab) [pubmed|28189581]
GP1824 (''[gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]''::''erm'', available in [wiki|Jörg Stülke]'s lab)
BKE38850 ([gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAAAAAGTTACGTTGAT, downstream forward: _UP4_TAACAGCTAACAAGGGTGCC
BKK38850 ([gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAAAAAGTTACGTTGAT, downstream forward: _UP4_TAACAGCTAACAAGGGTGCC
References
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Time of last update: 2024-04-19 15:06:27
Author of last update: Jstuelk