chrS

chrS
168

transcriptional repressor ([wiki|Lrp family]) of the [gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]-[gene|E63704C51B53F05BAD9B35D3B6874DB9231B6D24|ywrB]-[gene|70CC5C9BCC676AB89C0BF80686BD98BA08FAE648|ywrA] operon

locus
BSU_36110
Molecular weight
17.98 kDa
pI
5.84
Protein length
Gene length
function
regulation of chromate export
product
transcriptional repressor ([wiki|Lrp family])
essential
no
synonyms
chrS, ywrC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1522 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,720,925 → 3,721,401
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The protein
Protein family
[wiki|Lrp family]
[wiki|Domains]
[wiki|HTH asnC-type domain] (aa 12-73) (according to UniProt)
Structure
[PDB|1RI7] (from Pyrococcus sp., 31% identity) [pubmed|14976242]
[AF|O05217]
Expression and Regulation
Operons
genes
[gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]-[gene|E63704C51B53F05BAD9B35D3B6874DB9231B6D24|ywrB]-[gene|70CC5C9BCC676AB89C0BF80686BD98BA08FAE648|ywrA]
description
[Pubmed|22383849]
regulatory mechanism
[protein|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]: repression, [Pubmed|23989926], in [regulon|protein:C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|23989926], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]→[gene|70CC5C9BCC676AB89C0BF80686BD98BA08FAE648|ywrA]

2024-01-27 01:21:24

ghost

40

2f5d284c025e5da3cf0b383cdc78b2f7d2059416

0CB823E68942648C92CEAE3C88F594984EF4A6A2

Biological materials
Mutant
MGNA-A533 (ywrC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/533 NBRP B. subtilis, Japan]
BKE36110 (Δ[gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE36110 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATTGCTCCACCTGCTTTC,  downstream forward: _UP4_ATGAAGCTGTAAAGGAGAGA
BKK36110 (Δ[gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK36110 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATTGCTCCACCTGCTTTC,  downstream forward: _UP4_ATGAAGCTGTAAAGGAGAGA
References
Research papers
14976242

C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A

Page visits: 2104

Time of last update: 2024-03-27 11:51:19

Author of last update: Melvin.boenninger