yvgN
168
glyoxal reductase, general stress protein
locus
BSU_33400
Molecular weight
31.51 kDa
pI
5.07
function
unknown
product
glyoxal reductase
essential
no
ec
1.1.1.283
synonyms
yvgN, yvsB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0656 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,426,749 3,427,579
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The protein
Catalyzed reaction/ biological activity
Lactaldehyde + NADP+ --> methylglyoxal + NADPH (according to UniProt)
Protein family
[wiki|Aldo/keto reductase family] (according to UniProt)
[wiki|Cofactors]
NADP+ [pubmed|31165224]
Structure
[PDB|3B3E] [Pubmed|19585557]
[AF|O32210]
Paralogous protein(s)
[protein|DE12190315DADF13DA1BA272924729BBF909B1D9|ytbE]
Expression and Regulation
Operons
genes
[gene|994D5A36AECC75F5D0B59F7755BC5DB935ED6CE8|yvgN]
description
[pubmed|22383849]
regulatory mechanism
[protein|5A6FBAE6553343092862CB79E150F934978C32A9|sinR]: repression, [Pubmed|16430695], in [regulon|protein:5A6FBAE6553343092862CB79E150F934978C32A9|sinR regulon]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
MGNA-B061 (yvgN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1060 NBRP B. subtilis, Japan]
BKE33400 ([gene|994D5A36AECC75F5D0B59F7755BC5DB935ED6CE8|yvgN]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTGAACCTCCACCCTTT, downstream forward: _UP4_TAATCAAAAAACTCCCCGTT
BKK33400 ([gene|994D5A36AECC75F5D0B59F7755BC5DB935ED6CE8|yvgN]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTGAACCTCCACCCTTT, downstream forward: _UP4_TAATCAAAAAACTCCCCGTT
References
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Time of last update: 2024-04-19 02:35:11
Author of last update: Melvin.boenninger