cotU
168
outer spore coat protein
locus
BSU_17670
Molecular weight
11.42 kDa
pI
6.32
function
resistance of the spore
product
outer spore coat protein
essential
no
synonyms
cotU, ynzH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
1,901,117 → 1,901,377
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The protein
Structure
[AF|O31802]
Paralogous protein(s)
[protein|9C59B51FC19FC83BD14272008BD441833DD1738E|cotC]
[wiki|Localization]
outer spore coat, localization depends on [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|cotE] [Pubmed|22171814]
the [protein|9C59B51FC19FC83BD14272008BD441833DD1738E|cotC]-[protein|EB690FA075EAC3E298C47AED082B5FC21E8F8F46|cotU] complex assembles around the forming spore [Pubmed|18065538]
Expression and Regulation
Operons
genes
[gene|EB690FA075EAC3E298C47AED082B5FC21E8F8F46|cotU]
description
[Pubmed|22383849]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|18065538]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|18065538], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
[protein|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]: repression, [Pubmed|20435725], in [regulon|protein:0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|18065538], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
Biological materials
Mutant
MGNA-A021 (ynzH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/21 NBRP B. subtilis, Japan]
BKE17670 (Δ[gene|EB690FA075EAC3E298C47AED082B5FC21E8F8F46|cotU]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTAAATTCCTCCTTTAT, downstream forward: _UP4_TAAATCTCTTAAACGTCTAT
BKK17670 (Δ[gene|EB690FA075EAC3E298C47AED082B5FC21E8F8F46|cotU]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTAAATTCCTCCTTTAT, downstream forward: _UP4_TAAATCTCTTAAACGTCTAT
References
Reviews
Original Publications
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Time of last update: 2024-04-17 15:37:24
Author of last update: Jstuelk