thiU

thiU
168

thiamine [wiki|ECF transporter] (binding protein)

locus
BSU_13240
Molecular weight
21.88 kDa
pI
6.05
Protein length
Gene length
function
thiamine uptake
product
thiamine [wiki|ECF transporter] (binding protein)
essential
no
synonyms
thiU, ykoF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
1,391,040  1,391,642
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The protein
Structure
[PDB|1SBR] (complex with thiamine),  [PDB|1S99]
[AF|O34911]
[wiki|Localization]
membrane associated (via [protein|9AF27E4CE34B5C4036840A27D93B13213E3324DD|thiV]-[protein|236095EDE02EC9EA7768D9D30CED2345D3B7A1A9|thiX]) [Pubmed|16291685]
Expression and Regulation
Operons
genes
[gene|57A953B5D71F3FD8269EAF2366B8E2C7A8C79483|thiU]-[gene|9AF27E4CE34B5C4036840A27D93B13213E3324DD|thiV]-[gene|EF69891D9CF0CE57367B38FB3C69DDE1B689FCB7|thiW]-[gene|236095EDE02EC9EA7768D9D30CED2345D3B7A1A9|thiX]
description
[Pubmed|16291685]
regulation
repressed by thiamine ([protein|search|Thi-box]) [Pubmed|12376536]
regulatory mechanism
[protein|E195900D971AEE4A790D4579BE5E5A15B81010B8|Thi-box]: RNA switch, via [wiki|RNA switch], in [regulon|protein:E195900D971AEE4A790D4579BE5E5A15B81010B8|Thi-box regulon]
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[gene|57A953B5D71F3FD8269EAF2366B8E2C7A8C79483|thiU]→[gene|236095EDE02EC9EA7768D9D30CED2345D3B7A1A9|thiX]

2024-02-15 03:52:57

ghost

46

a5e5cadfad9e042a2adaaf16b65a4c80dd95df3c

9641459E0C11D1D42D24F1497F3D70BD345B9DA1

Biological materials
Mutant
MGNA-A757 (ykoF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/757 NBRP B. subtilis, Japan]
BKK13240 ([gene|57A953B5D71F3FD8269EAF2366B8E2C7A8C79483|thiU]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK13240 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCTCCGACCTCCTGTT,  downstream forward: _UP4_AGAAAAAACAGAAAGCAGGG
References
16291685,12376536,15451668

57A953B5D71F3FD8269EAF2366B8E2C7A8C79483

Page visits: 1873

Time of last update: 2024-03-29 11:52:02

Author of last update: Jstuelk