xylA

xylA
168

xylose isomerase

locus
BSU_17600
Molecular weight
50.09 kDa
pI
5.64
Protein length
Gene length
function
utilization of xylan and xylose
product
xylose isomerase
essential
no
ec
5.3.1.5
synonyms
xylA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2115 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,891,908  1,893,245
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The protein
Catalyzed reaction/ biological activity
D-xylose --> D-xylulose
Protein family
xylose isomerase family (according to Swiss-Prot)
Structure
[PDB|1A0D] (Geobacillus stearothermophilus)
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|24829427B4518FE67038F194B54D4AAFAC64EF19|xylA]-[gene|F417A5B46CC7FC69DC8606A46D1AD5E41FA35B13|xylB]
description
[Pubmed|1921970]
regulation
carbon catabolite repression ([protein|search|CcpA]) [Pubmed|8132469]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|8132469], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|AF4395D134485290F4AA307B48494FED39E52CD7|xylR]: repression, [Pubmed|2454911], in [regulon|protein:AF4395D134485290F4AA307B48494FED39E52CD7|xylR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|2454911], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|24829427B4518FE67038F194B54D4AAFAC64EF19|xylA]→[gene|F417A5B46CC7FC69DC8606A46D1AD5E41FA35B13|xylB]

2024-03-06 21:09:56

ghost

60

03ab48d2da7656afb5bebb25c49c9a7a060c0932

CFA5B475783918BA5946A0FB73EFAFE093A8416B

Biological materials
Mutant
GP1151 (del aphA3) available in [wiki|Jörg Stülke]'s lab
1A719 (no resistance), [Pubmed|1719948], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A719&Search=1A719 BGSC]
BKE17600 ([gene|24829427B4518FE67038F194B54D4AAFAC64EF19|xylA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17600 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTGATTTCCCCCTTAAA,  downstream forward: _UP4_TAACAGGATAAGCTCCAGAT
BKK17600 ([gene|24829427B4518FE67038F194B54D4AAFAC64EF19|xylA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17600 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTGATTTCCCCCTTAAA,  downstream forward: _UP4_TAACAGGATAAGCTCCAGAT
References
7966270,1921970,8132469,2454911,1588910,22900538

24829427B4518FE67038F194B54D4AAFAC64EF19

Page visits: 5283

Time of last update: 2024-03-28 19:37:25

Author of last update: Christoph.elfmann