spoIIID

spoIIID
168

transcriptional regulator (repressor or activator) of a subset of [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigma E]-dependent genes

locus
BSU_36420
Molecular weight
10.66 kDa
pI
9.5
Protein length
Gene length
function
regulation of mother cell gene expression
product
transcriptional regulator
essential
no
synonyms
spoIIID

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5830 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,748,421  3,748,702
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The protein
Catalyzed reaction/ biological activity
binds its DNA targets as a monomeric protein (possible due to the two DNA-binding motifs) [Pubmed|20061473]
[wiki|Domains]
two DNA-binding regions: HTH at the N-terminus and a basic region near the C-terminus [Pubmed|20061473]
[wiki|HTH deoR-type domain] (aa 4-75) (according to UniProt)
Structure
[PDB|2L0K] (complex with DNA)
[AF|P15281]
Expression and Regulation
Operons
genes
[gene|487990143C84D245743C0014E648699627204FF0|usd]-[gene|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]-[gene|6ED386D49F973C1F6B1076974F54275DD583C9D3|mbl]
description
[Pubmed|22383849]
regulation
expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|9023218].
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|9023218], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
additional information
An antisense RNA is predicted for '[protein|search|mbl]' [PubMed|20525796]
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[gene|487990143C84D245743C0014E648699627204FF0|usd]→[gene|6ED386D49F973C1F6B1076974F54275DD583C9D3|mbl]

2024-01-25 06:11:58

ghost

54

28c9ae47f591b2fa42d0b7f03ef68a6e6e5610b4

F750C9E92E1FA0FEB7B1C7A4992F6482308F0F6F

Biological materials
Mutant
BKE36420 ([gene|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE36420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_ATCGTGCACACCACTCGACC,  downstream forward: _UP4_TAATCACCTGGCATTGCCTT
BKK36420 ([gene|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK36420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_ATCGTGCACACCACTCGACC,  downstream forward: _UP4_TAATCACCTGGCATTGCCTT
References
Reviews
31350897,35638784
Original Publications
15383836,1469717,7896717,1900494,8231808,9023218,2112673,1691789,10788508,1744038,7966271,2514119,1518043,17693505,9006059,20061473,17890309,17693499,7836311,24584501,22463703,30953122

90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397

Page visits: 3967

Time of last update: 2024-03-28 15:02:22

Author of last update: Jstuelk