secG
168
preprotein translocase subunit
locus
BSU_33630
Molecular weight
7.86 kDa
pI
10.41
function
protein secretion
product
preprotein translocase subunit
essential
no
synonyms
secG, yvaL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1314 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,455,093 → 3,455,323
Phenotypes of a mutant
reduced [wiki|protein secretion] [pubmed|32111210]
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The protein
Protein family
secG family (single member, according to UniProt)
Structure
[PDB|3DL8] (structure of the ([protein|5350DC618130E013757EE667B9AFC5F2EC68EC08|secY]-[protein|1007EA15FB7AF81A44400287DB68BCC497158ACF|secE]-[protein|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG])-[protein|AD7CD451B4AE638A719C91780339784A7FF0F248|secA] complex) [Pubmed|18923516]
[AF|O32233]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG]-[gene|C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8|yvaK]-[gene|0472A4346ADA1DC41C9D00E8F3222A0EBB76DFA8|rnr]-[gene|D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A|smpB]-[gene|5C12BB19B975F7FEBCFA119DAC66338C20FCECFA|ssrA]
description
[Pubmed|17369301]
regulation
''[protein|search|yvaK]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
BKE33630 (Δ[gene|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCCATACACCTCCAGAC, downstream forward: _UP4_TAGGGCAATGTTTGTATAAG
BKK33630 (Δ[gene|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCCATACACCTCCAGAC, downstream forward: _UP4_TAGGGCAATGTTTGTATAAG
References
Reviews
Original Publications
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Time of last update: 2024-04-14 17:16:34
Author of last update: Jstuelk