ppsB

ppsB
168

plipastatin synthetase

locus
BSU_18330
Molecular weight
289.84 kDa
pI
5.06
Protein length
Gene length
function
production of the antibacterial compound plipastatin
product
plipastatin synthetase
essential
no
synonyms
ppsB

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3433 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,982,565 → 1,990,247
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The protein
Protein family
[wiki|ATP-dependent AMP-binding enzyme family] (according to UniProt)
[wiki|Domains]
2 [wiki|Carrier domain]s (aa 965-1040, aa 2006-2080) (according to UniProt)
Structure
[PDB|2VSQ] (termination module of [protein|1D5F227860A321506A1AB4BAE63CAD3A66E43BFC|srfAC], 38% identity) [pubmed|18583577]
[AF|P39846]
Expression and Regulation
Operons
genes
[gene|E3D7EF8F165CAC2682B0D620081C5C6E555E43C4|ppsA]-[gene|E7A2F93B33B1899313893D362D92405232BC9097|ppsB]-[gene|D11CE89E2AC2ADE3FEFEC261E295EC5906CE6407|ppsC]-[gene|E73D9F1A8F54DAD4B2056CABBE580D7AD36CB042|ppsD]-[gene|C1C051209943E02369356075EAA733297E9478CB|ppsE]
description
[Pubmed|20817675]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
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[gene|E3D7EF8F165CAC2682B0D620081C5C6E555E43C4|ppsA]→[gene|C1C051209943E02369356075EAA733297E9478CB|ppsE]

2024-02-29 22:40:06

ghost

55

c24e95905169206a2bb4f32c2e44eb72392e19bb

53EB981BAF3A634ABF820E4DAD645D458FD52A47

Biological materials
Mutant
BKE18330 (Δ[gene|E7A2F93B33B1899313893D362D92405232BC9097|ppsB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE18330 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCAATTCCACACACCTTT,  downstream forward: _UP4_AAACTATAGGAGAGGAGATT
BKK18330 (Δ[gene|E7A2F93B33B1899313893D362D92405232BC9097|ppsB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK18330 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCAATTCCACACACCTTT,  downstream forward: _UP4_AAACTATAGGAGAGGAGATT
References
10471562,9387222,20817675,18583577

E7A2F93B33B1899313893D362D92405232BC9097

Page visits: 5228

Time of last update: 2024-03-28 19:38:02

Author of last update: Melvin.boenninger