lrpC
168
sequence-independent DNA-binding and DNA-bending protein (Lrp family), facilitates the formation of higher order protein-DNA complexes
locus
BSU_04250
Molecular weight
16.31 kDa
pI
7.74
function
DNA repair/ recombination
product
DNA-binding and -bending protein
essential
no
synonyms
lrpC, ydaI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1522 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
476,059 476,493
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The protein
Protein family
([wiki|Lrp family])
[wiki|Domains]
[wiki|HTH asnC-type domain] (aa 3-64) (according to UniProt)
Structure
[PDB|2CFX] [pubmed|16528101]
[AF|P96582]
Expression and Regulation
Operons
genes
[gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]-[gene|7D5327BD1DD5FD5F90B2C849589923AA3D8B20EF|topB]
description
[pubmed|22383849]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [pubmed|10913073], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
50 ... 300 molecules per cell [PubMed|10913073]
Biological materials
Mutant
GP3567 (Δ[gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]::aphA3), available in [wiki|Jörg Stülke]'s lab
MGNA-C106 (ydaI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2104 NBRP B. subtilis, Japan]
BKE04250 ([gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACATCCTTCTTTT, downstream forward: _UP4_TAGAGAGTGCCGCGCGAAGT
BKK04250 ([gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACATCCTTCTTTT, downstream forward: _UP4_TAGAGAGTGCCGCGCGAAGT
References
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Time of last update: 2024-04-18 23:18:00
Author of last update: Jstuelk