kduI

kduI
168

5-keto-4-deoxyuronate isomerase

locus
BSU_22130
Molecular weight
30.98 kDa
pI
5.11
Protein length
Gene length
function
utilization of galacturonic acid
product
5-keto-4-deoxyuronate isomerase
essential
no
ec
5.3.1.17
synonyms
kduI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3717 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,325,854 → 2,326,681
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The protein
Catalyzed reaction/ biological activity
5-dehydro-4-deoxy-D-glucuronate --> 3-deoxy-D-glycero-2,5-hexodiulosonate (according to UniProt)
Protein family
KduI family (single member, according to UniProt)
Structure
[PDB|1YWK] (from Enterococcus faecalis, 48% identity)
[AF|P50843]
Expression and Regulation
Operons
genes
[gene|CFAEF60AD73F18C8DB5EF042210602B149D51152|kduI]-[gene|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|kduD]
description
[Pubmed|17322190]
regulation
induced by galacturonate ([protein|search|KdgR]) [Pubmed|17322190]
regulatory mechanism
[protein|891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR]: repression, [Pubmed|17322190], in [regulon|protein:891A32A19D1353BA566FF121BBCA7B986D31D129|kdgR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|17322190], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|17322190], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|CFAEF60AD73F18C8DB5EF042210602B149D51152|kduI]→[gene|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|kduD]

2024-03-03 11:05:00

ghost

49

4a8739bc6783690fc74587a3d4541c259279a581

B77865E5AAA4E592F977DA1B986CD2525D071736

Biological materials
Mutant
BKE22130 (Δ[gene|CFAEF60AD73F18C8DB5EF042210602B149D51152|kduI]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22130 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATATTTCCCCCTTGGT,  downstream forward: _UP4_ATTCCAATGGATGGGCTGAA
BKK22130 (Δ[gene|CFAEF60AD73F18C8DB5EF042210602B149D51152|kduI]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22130 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATATTTCCCCCTTGGT,  downstream forward: _UP4_ATTCCAATGGATGGGCTGAA
References
17322190

CFAEF60AD73F18C8DB5EF042210602B149D51152

Page visits: 1676

Time of last update: 2024-03-23 14:19:18

Author of last update: Melvin.boenninger