galT
168
galactose-1-phosphate uridylyltransferase
locus
BSU_38190
Molecular weight
58.44 kDa
pI
5.62
function
galactose utilization
product
galactose-1-phosphate uridylyltransferase
essential
no
ec
2.7.7.12
synonyms
galT, ipa-36d
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4468 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,919,093 3,920,634
Advertisement
The protein
Catalyzed reaction/ biological activity
α-D-galactose 1-phosphate + UDP-α-D-glucose --> α-D-glucose 1-phosphate + UDP-α-D-galactose (according to UniProt)
Protein family
galactose-1-phosphate uridylyltransferase type 2 family (single member, according to UniProt)
Structure
[AF|P39575]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|36930CC6FDFCA23D43E264FEA375B78A1434E1BD|galK]-[gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]
description
[Pubmed|9353933]
regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|10666464], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
genes
[gene|C3D87DAA8DB124D50D2C2B2D424C9608C0DE067F|ywcC]-[gene|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|gtcA]-[gene|36930CC6FDFCA23D43E264FEA375B78A1434E1BD|galK]-[gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]
description
[Pubmed|22383849,22893383]
regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
Biological materials
Mutant
BKE38190 ([gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38190 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAGATGTTCAATAATACTCA, downstream forward: _UP4_TAGGGTTGAGGCTTTTTCGA
BKK38190 ([gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38190 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAGATGTTCAATAATACTCA, downstream forward: _UP4_TAGGGTTGAGGCTTTTTCGA
References
Page visits: 2728
Time of last update: 2024-04-19 16:54:09
Author of last update: Melvin.boenninger