fruK
168
fructose-1-phosphate kinase
locus
BSU_14390
Molecular weight
32.64 kDa
pI
4.89
function
fructose utilization
product
fructose-1-phosphate kinase
essential
no
ec
2.7.1.56
synonyms
fruK, fruB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1105 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,508,330 1,509,241
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The protein
Catalyzed reaction/ biological activity
ATP + β-D-fructose 1-phosphate --> ADP + β-D-fructose 1,6-bisphosphate + H+ (according to UniProt)
Protein family
[wiki|carbohydrate kinase PfkB family] (according to UniProt)
Structure
[PDB|3OHR]
[AF|O31714]
Expression and Regulation
Operons
genes
[gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]-[gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]-[gene|973C3D3FBFDCA095A760C5F49A96D8BE48771014|fruA]
description
[pubmed|22383849]
regulation
induced in the presence of fructose ([protein|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]) (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS])
regulatory mechanism
[protein|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]: repression, (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS]), in [regulon|protein:7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR regulon]
Biological materials
Mutant
BKE14390 ([gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGGATTAAGTGTTACAGTGT, downstream forward: _UP4_CGTCTATAGAGGAGGAAACA
BKK14390 ([gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGGATTAAGTGTTACAGTGT, downstream forward: _UP4_CGTCTATAGAGGAGGAAACA
References
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Time of last update: 2024-04-16 17:29:03
Author of last update: Melvin.boenninger