bglC
168
endo-1,4-beta-glucanase
locus
BSU_18130
Molecular weight
55.12 kDa
pI
8.62
function
beta-1,4-glucan degradation
product
endo-1,4-beta-glucanase)
essential
no
ec
3.2.1.4
synonyms
bglC, eglS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2730 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,940,625 → 1,942,124
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The protein
Catalyzed reaction/ biological activity
Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans (according to UniProt)
Protein family
glycosyl hydrolase 5 (cellulase A) family (single member, according to UniProt)
[wiki|Domains]
CBM3 domain (aa 350-499) (according to UniProt)
Structure
[PDB|3PZT] [Pubmed|21880019]
[AF|P10475]
[wiki|Localization]
extracellular (signal peptide) [Pubmed|18957862]
Expression and Regulation
Operons
genes
[gene|B0528C4772B2357D10AEEA3C63080C5176B27E7B|bglC]
description
[pubmed|22383849]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|3106328], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
1A751 (no resistance), [Pubmed|7704256], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A751&Search=1A751 BGSC]
1A752 (no resistance), [Pubmed|7704256], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A752&Search=1A752 BGSC]
1A976 (no resistance), [Pubmed|21255377], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A976&Search=1A976 BGSC]
BKE18130 (Δ[gene|B0528C4772B2357D10AEEA3C63080C5176B27E7B|bglC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE18130 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCTGATCTTTTCCTCC, downstream forward: _UP4_TAGTTAAGCTTTTTTTTGGC
BKK18130 (Δ[gene|B0528C4772B2357D10AEEA3C63080C5176B27E7B|bglC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK18130 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCTGATCTTTTCCTCC, downstream forward: _UP4_TAGTTAAGCTTTTTTTTGGC
References
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Time of last update: 2024-04-18 14:46:10
Author of last update: Jstuelk