iolQ

iolQ
168

transcriptional repressor of [gene|AA7DCEFB17FD6F9C4F65235E9A247A6EC2242B06|iolX] expression, transcriptional activator involved in the degradation of glutamine phosphoribosylpyrophosphate amidotransferase

locus
BSU_10840
Molecular weight
36.44 kDa
pI
5.78
Protein length
Gene length
function
control of scyllo-inositol utilization
product
transcription factor ([wiki|LacI family])
essential
no
synonyms
iolQ, degA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,163,148  1,164,161
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The protein
Catalyzed reaction/ biological activity
binds to [gene|AA7DCEFB17FD6F9C4F65235E9A247A6EC2242B06|iolX] promoter region [pubmed|28693424]
[wiki|Domains]
[wiki|HTH lacI-type domain] (aa 1-57) (according to UniProt)
Structure
[PDB|2HSG] ([protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA], 35% identity) [pubmed|17500051]
[AF|P37947]
Expression and Regulation
Operons
genes
[gene|5B173B400D0B4C150E94A98D35E27B0B4358489B|yisR]-[gene|17F5188958A415D8D09439E02E1D1E0661B5C760|iolQ]
description
[pubmed|22383849]
Open in new tab

[gene|5B173B400D0B4C150E94A98D35E27B0B4358489B|yisR]→[gene|17F5188958A415D8D09439E02E1D1E0661B5C760|iolQ]

2024-02-27 08:49:21

Jstuelk

51

7438187f03d36037b5df0669313f550962ddaa97

74E985CFB3A7C6E9A585316B0701C0F3EEE303EE

additional information
the mRNA is very stable (> 15 min) [pubmed|12884008]
Biological materials
Mutant
BKE10840 ([gene|17F5188958A415D8D09439E02E1D1E0661B5C760|iolQ]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10840 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTCATGTTCATCCCTCGTC,  downstream forward: _UP4_TGAGCCCGCTAATGAGCGGG
BKK10840 ([gene|17F5188958A415D8D09439E02E1D1E0661B5C760|iolQ]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10840 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTCATGTTCATCCCTCGTC,  downstream forward: _UP4_TGAGCCCGCTAATGAGCGGG
References
8407808,12884008,28693424,33320079

17F5188958A415D8D09439E02E1D1E0661B5C760

Page visits: 3121

Time of last update: 2024-03-28 15:19:07

Author of last update: Jstuelk