yisP

yisP
168

farnesyl diphosphate phosphatase, production of farnesol

locus
BSU_10810
Molecular weight
31.35 kDa
pI
7.26
Protein length
Gene length
function
control of [protein|A656321846B2E0D1F39B528E2D8B8E620CCD1148|kinC] activity
product
farnesyl diphosphate phosphatase
essential
no
synonyms
yisP, yucD

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1562 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,159,922 → 1,160,746
Phenotypes of a mutant
complete loss of pellicle-forming ability [Pubmed|20713508]
reduced [wiki|protein secretion] [Pubmed|23651456]
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The protein
Catalyzed reaction/ biological activity
farnesyl diphosphate -→ farnesol [Pubmed|25308276]
Protein family
phytoene/squalene synthase family (single member, according to UniProt)
[wiki|Cofactors]
NADH  [Pubmed|20713508]
Structure
[PDB|3WE9] [Pubmed|25308276]
[AF|O06728]
Expression and Regulation
Operons
genes
[gene|E5F32D960F6FF50A7B0E4B268D2296FE1A291512|yisP]
description
[pubmed|22383849]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|26577401], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
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[gene|E5F32D960F6FF50A7B0E4B268D2296FE1A291512|yisP]

2024-02-18 14:29:22

Bzhu

37

a6c0ff69b7b98c2b56b2dc5864332cfc64caba3f

7EBA26BD2FD60B54DD6D859BBF845DB2802B0AB2

Biological materials
Mutant
MGNA-B190 (yisP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1189 NBRP B. subtilis, Japan]
BKE10810 (Δ[gene|E5F32D960F6FF50A7B0E4B268D2296FE1A291512|yisP]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10810 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACTGCTTCTTCAAGTCTAG,  downstream forward: _UP4_TAAAAAACACCCGGCCTTGA
BKK10810 (Δ[gene|E5F32D960F6FF50A7B0E4B268D2296FE1A291512|yisP]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10810 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACTGCTTCTTCAAGTCTAG,  downstream forward: _UP4_TAAAAAACACCCGGCCTTGA
References
Reviews
25457121,25652542
Original Publications
20713508,19935659,23651456,23295493,25308276,26577401

E5F32D960F6FF50A7B0E4B268D2296FE1A291512

Page visits: 2639

Time of last update: 2024-03-28 08:20:53

Author of last update: Jstuelk