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Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

AbrB regulon, CcpA regulon


  • Coordinates on the chromosome (coding sequence): 3,701,411 -> 3,702,391
  • The protein

    Catalyzed reaction/ biological activity

    Protein family

  • LacI family
  • Paralogous protein(s)

    Kinetic information




    Effectors of protein activity




  • PtsH-RbsR PubMed
  • Additional information

    Expression and Regulation


  • rbsR-rbsK-rbsD-rbsA-rbsC-rbsB PubMed
  • Sigma factor

  • SigA PubMed
  • Regulation

  • repressed by glucose (10-fold) (CcpA) PubMed
  • expressed upon transition into the stationary phase (AbrB) PubMed
  • Regulatory mechanism

  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed
  • Additional information

    Biological materials


    Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Marciniak BC, Pabijaniak M, de Jong A, Dűhring R, Seidel G, Hillen W, Kuipers OP

    High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis

    BMC Genomics. 2012 Aug 17;13:401. doi: 10.1186/1471-2164-13-401. PubMed PMID: 22900538; PubMed Central PMCID: PMC3463425.
    Tam le T, Eymann C, Albrecht D, Sietmann R, Schauer F, Hecker M, Antelmann H

    Differential gene expression in response to phenol and catechol reveals different metabolic activities for the degradation of aromatic compounds in Bacillus subtilis

    Environ Microbiol. 2006 Aug;8(8):1408-27. PubMed PMID: 16872404.
    Müller W, Horstmann N, Hillen W, Sticht H

    The transcription regulator RbsR represents a novel interaction partner of the phosphoprotein HPr-Ser46-P in Bacillus subtilis

    FEBS J. 2006 Mar;273(6):1251-61. PubMed PMID: 16519689.
    Blencke HM, Homuth G, Ludwig H, Mäder U, Hecker M, Stülke J

    Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways

    Metab Eng. 2003 Apr;5(2):133-49. PubMed PMID: 12850135.
    Woodson K, Devine KM

    Analysis of a ribose transport operon from Bacillus subtilis

    Microbiology. 1994 Aug;140 ( Pt 8):1829-38. PubMed PMID: 7921236.
    Strauch MA

    AbrB modulates expression and catabolite repression of a Bacillus subtilis ribose transport operon

    J Bacteriol. 1995 Dec;177(23):6727-31. PubMed PMID: 7592460; PubMed Central PMCID: PMC177535.
    O'Reilly M, Woodson K, Dowds BC, Devine KM

    The citrulline biosynthetic operon, argC-F, and a ribose transport operon, rbs, from Bacillus subtilis are negatively regulated by Spo0A

    Mol Microbiol. 1994 Jan;11(1):87-98. PubMed PMID: 7511775.
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