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Categories containing this gene/protein

cell wall degradation/ turnover, phosphotransferase systems, utilization of specific carbon sources, membrane proteins, phosphoproteins

This gene is a member of the following regulons

GamR regulon


  • Coordinates on the chromosome (coding sequence): 254,907 -> 256,802
  • Phenotypes of a mutant

  • delayed growth with glucosamine as the single carbon source PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
  • Protein family

  • PTS permease, glucose permease (Glc) family PubMed
  • Paralogous protein(s)

  • NagP
  • Kinetic information




    Effectors of protein activity



  • membrane PubMed
  • Interactions

  • GamP-HPr
  • Additional information

    Expression and Regulation


  • gamA-gamP PubMed
  • Sigma factor

  • SigA PubMed
  • Regulation

  • induced by glucosamine (GamR) PubMed
  • Regulatory mechanism

  • GamR: transcription repression PubMed
  • Additional information

    Biological materials


  • MGNA-B937 (ybfS::erm), available at the NBRP B. subtilis, Japan
  • QB6098 (aphA3), available in Stülke lab
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Gaugué I, Oberto J, Plumbridge J

    Regulation of amino sugar utilization in Bacillus subtilis by the GntR family regulators, NagR and GamR

    Mol Microbiol. 2014 Apr;92(1):100-15. doi: 10.1111/mmi.12544. Epub 2014 Mar 5. PubMed PMID: 24673833.
    Gaugué I, Oberto J, Putzer H, Plumbridge J

    The use of amino sugars by Bacillus subtilis: presence of a unique operon for the catabolism of glucosamine

    PLoS One. 2013 May 8;8(5):e63025. doi: 10.1371/journal.pone.0063025. Print 2013. PubMed PMID: 23667565; PubMed Central PMCID: PMC3648570.
    Hahne H, Wolff S, Hecker M, Becher D

    From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches

    Proteomics. 2008 Oct;8(19):4123-36. doi: 10.1002/pmic.200800258. PubMed PMID: 18763711.
    Reizer J, Bachem S, Reizer A, Arnaud M, Saier MH Jr, Stülke J

    Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis

    Microbiology. 1999 Dec;145 ( Pt 12):3419-29. PubMed PMID: 10627040.
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